diff --git a/src/cmd/compile/internal/ssa/gen/RISCV64.rules b/src/cmd/compile/internal/ssa/gen/RISCV64.rules
index 4380a5e..1d3e738 100644
--- a/src/cmd/compile/internal/ssa/gen/RISCV64.rules
+++ b/src/cmd/compile/internal/ssa/gen/RISCV64.rules
@@ -249,7 +249,7 @@
 (Leq64F ...) => (FLED ...)
 (Leq32F ...) => (FLES ...)
 
-(EqPtr x y) => (SEQZ (SUB <x.Type> x y))
+(EqPtr x y) => (SEQZ (SUB <typ.Uintptr> x y))
 (Eq64  x y) => (SEQZ (SUB <x.Type> x y))
 (Eq32  x y) => (SEQZ (SUBW <x.Type> x y))
 (Eq16  x y) => (SEQZ (SUB <x.Type> (ZeroExt16to64 x) (ZeroExt16to64 y)))
@@ -257,7 +257,7 @@
 (Eq64F ...) => (FEQD ...)
 (Eq32F ...) => (FEQS ...)
 
-(NeqPtr x y) => (SNEZ (SUB <x.Type> x y))
+(NeqPtr x y) => (SNEZ (SUB <typ.Uintptr> x y))
 (Neq64  x y) => (SNEZ (SUB <x.Type> x y))
 (Neq32  x y) => (SNEZ (SUBW <x.Type> x y))
 (Neq16  x y) => (SNEZ (SUB <x.Type> (ZeroExt16to64 x) (ZeroExt16to64 y)))
diff --git a/src/cmd/compile/internal/ssa/rewriteRISCV64.go b/src/cmd/compile/internal/ssa/rewriteRISCV64.go
index fb507b6..a34b59d 100644
--- a/src/cmd/compile/internal/ssa/rewriteRISCV64.go
+++ b/src/cmd/compile/internal/ssa/rewriteRISCV64.go
@@ -960,13 +960,14 @@
 	v_1 := v.Args[1]
 	v_0 := v.Args[0]
 	b := v.Block
+	typ := &b.Func.Config.Types
 	// match: (EqPtr x y)
-	// result: (SEQZ (SUB <x.Type> x y))
+	// result: (SEQZ (SUB <typ.Uintptr> x y))
 	for {
 		x := v_0
 		y := v_1
 		v.reset(OpRISCV64SEQZ)
-		v0 := b.NewValue0(v.Pos, OpRISCV64SUB, x.Type)
+		v0 := b.NewValue0(v.Pos, OpRISCV64SUB, typ.Uintptr)
 		v0.AddArg2(x, y)
 		v.AddArg(v0)
 		return true
@@ -2519,13 +2520,14 @@
 	v_1 := v.Args[1]
 	v_0 := v.Args[0]
 	b := v.Block
+	typ := &b.Func.Config.Types
 	// match: (NeqPtr x y)
-	// result: (SNEZ (SUB <x.Type> x y))
+	// result: (SNEZ (SUB <typ.Uintptr> x y))
 	for {
 		x := v_0
 		y := v_1
 		v.reset(OpRISCV64SNEZ)
-		v0 := b.NewValue0(v.Pos, OpRISCV64SUB, x.Type)
+		v0 := b.NewValue0(v.Pos, OpRISCV64SUB, typ.Uintptr)
 		v0.AddArg2(x, y)
 		v.AddArg(v0)
 		return true
diff --git a/test/fixedbugs/issue51101.go b/test/fixedbugs/issue51101.go
new file mode 100644
index 0000000..a390e50
--- /dev/null
+++ b/test/fixedbugs/issue51101.go
@@ -0,0 +1,36 @@
+// run
+
+// Copyright 2022 The Go Authors. All rights reserved.
+// Use of this source code is governed by a BSD-style
+// license that can be found in the LICENSE file.
+
+// Issue 51101: on RISCV64, difference of two pointers
+// was marked as pointer and crashes GC.
+
+package main
+
+var a, b int
+
+func main() {
+	F(&b, &a)
+}
+
+//go:noinline
+func F(a, b *int) bool {
+	x := a == b
+	G(x)
+	y := a != b
+	return y
+}
+
+//go:noinline
+func G(bool) {
+	grow([1000]int{20})
+}
+
+func grow(x [1000]int) {
+	if x[0] != 0 {
+		x[0]--
+		grow(x)
+	}
+}